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Empty the stomach by inducing vomiting or by gastric lavage. Do not split, chew, or crush the tablet. Also take a medicine called tizanidine (Zanaflex ®). Cyprus Film Days International Festival, the largest international film event in Cyprus dedicated exclusivel. Geriatric: Increased risk for severe tendon disorders further increased by concomitant corticosteroid therapy; also increased risk of prolongation of the QT interval ( 8. Penetration of ciprofloxacin and metabolites into human lung, bronchial and pleural tissue after 250 and 500 mg oral ciprofloxacin. The pharmacokinetics of ciprofloxacin in patients with acute hepatic insufficiency, have not been studied. Also, two or more serious side effects can occur together, the FDA said.